Paulette Bioulac-Sage Selected Research

beta Catenin

1/2021	Predictive Patterns of Glutamine Synthetase Immunohistochemical Staining in CTNNB1-mutated Hepatocellular Adenomas.
1/2020	Clinical Impact of Genomic Diversity From Early to Advanced Hepatocellular Carcinoma.
8/2014	Pictures of focal nodular hyperplasia and hepatocellular adenomas.
8/2009	Hepatocellular adenoma management and phenotypic classification: the Bordeaux experience.
3/2009	Over-expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology.
1/2009	Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours.
12/2008	Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer.
9/2008	Hepatocellular adenomas: magnetic resonance imaging features as a function of molecular pathological classification.
7/2008	The beta-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules.
6/2008	MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations.

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Paulette Bioulac-Sage Research Topics

Disease

59	Neoplasms (Cancer) 01/2021 - 04/2003
42	Hepatocellular Carcinoma (Hepatoma) 01/2020 - 05/2002
39	Liver Cell Adenoma (Hepatocellular Adenoma) 01/2021 - 11/2003
14	Fibrosis (Cirrhosis) 10/2018 - 05/2002
13	Adenoma (Adenomas) 01/2020 - 04/2003
12	Focal Nodular Hyperplasia 01/2019 - 03/2003
11	Carcinogenesis 01/2017 - 03/2005
8	Hemorrhage 11/2021 - 08/2009
7	Carcinoma (Carcinomatosis) 01/2020 - 05/2005
5	Liver Neoplasms (Liver Cancer) 08/2017 - 04/2007
5	Inflammation (Inflammations) 05/2013 - 01/2006
3	Liver Diseases (Liver Disease) 01/2019 - 12/2006
3	Necrosis 01/2018 - 01/2008
3	Cholestasis 12/2017 - 05/2002
3	Glycogen Storage Disease (Glycogenosis) 04/2014 - 01/2008
3	Cholangiocarcinoma 03/2011 - 04/2007
3	Infections 06/2008 - 01/2002
2	Hepatoblastoma 01/2020 - 12/2008
2	Hepatitis C 01/2019 - 09/2005
2	Hypersensitivity (Allergy) 01/2019 - 02/2010
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2019 - 01/2019
2	Type 3 Maturity-Onset Diabetes of the Young 01/2013 - 11/2003
2	Obesity 09/2012 - 01/2008
2	Rectal Neoplasms (Rectal Cancer) 01/2008 - 05/2005
2	Chronic Hepatitis C 12/2006 - 06/2003
1	Non-alcoholic Fatty Liver Disease 01/2019

Drug/Important Bio-Agent (IBA)

22	CateninsIBA 11/2021 - 12/2010
18	beta CateninIBA 01/2021 - 08/2004
13	Oral ContraceptivesIBA 01/2019 - 03/2003
12	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2005
7	Glutamate-Ammonia Ligase (Glutamine Synthetase)IBA 01/2021 - 03/2009
6	Messenger RNA (mRNA)IBA 01/2020 - 04/2007
6	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2020 - 03/2005
6	Interleukin-6 (Interleukin 6)IBA 01/2016 - 01/2009
6	Hepatocyte Nuclear Factor 1-alpha (Hepatocyte Nuclear Factor 1 alpha)IBA 02/2010 - 11/2003
5	Hepatocyte Nuclear FactorsIBA 01/2020 - 03/2007
5	C-Reactive ProteinIBA 10/2019 - 01/2010
4	Sorafenib (BAY 43-9006)FDA Link 01/2020 - 12/2012
4	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 06/2004
4	Transcription Factors (Transcription Factor)IBA 02/2010 - 11/2004
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 12/2013
3	Fatty Acid-Binding ProteinsIBA 01/2020 - 03/2009
3	RNA (Ribonucleic Acid)IBA 01/2019 - 11/2009
3	ParaffinIBA 12/2017 - 04/2017
3	MicroRNAs (MicroRNA)IBA 01/2017 - 06/2008
3	Glutamine (L-Glutamine)FDA Link 12/2016 - 02/2008
3	Serum Amyloid A Protein (Serum Amyloid A)IBA 01/2016 - 03/2009
3	Hormones (Hormone)IBA 04/2014 - 01/2008
3	Protein Isoforms (Isoforms)IBA 01/2014 - 05/2007
3	Adenosine Triphosphatases (ATPase)IBA 12/2012 - 10/2007
2	ApolipoproteinsIBA 01/2020 - 09/2005
2	GlypicansIBA 01/2020 - 01/2013
2	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 10/2019 - 12/2017
2	gadolinium ethoxybenzyl DTPA FDA Link 01/2019 - 07/2013
2	CyclinsIBA 12/2018 - 10/2015
2	Cyclin A2IBA 12/2018 - 10/2015
2	Epithelial Cell Adhesion MoleculeIBA 10/2018 - 12/2013
2	Formaldehyde (Formol)FDA Link 12/2017 - 12/2017
2	Aflatoxin B1 (Aflatoxin B)IBA 11/2017 - 05/2015
2	Cytochrome P-450 CYP1A2 (CYP1A2)IBA 04/2017 - 03/2007
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 12/2016 - 06/2008
2	Fatty Acids (Saturated Fatty Acids)IBA 02/2013 - 05/2007
2	Colloids (Colloid)IBA 01/2013 - 05/2005
2	Small Interfering RNA (siRNA)IBA 10/2011 - 10/2007
2	IronIBA 04/2010 - 05/2005
2	Carbon Tetrachloride (Tetrachloromethane)IBA 01/2008 - 01/2007
2	Thrombin FDA Link 01/2008 - 01/2006
2	Fibrillin-1IBA 01/2004 - 05/2002
1	regorafenibIBA 01/2020
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020
1	Immunologic Factors (Immunomodulators)IBA 01/2020
1	AlbuminsIBA 01/2020
1	Apolipoproteins B (ApoB)IBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2019
1	micaIBA 01/2019
1	cabozantinibIBA 01/2019
1	Oxidoreductases (Dehydrogenase)IBA 01/2019
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2018
1	pgRNAIBA 01/2018
1	sodium-bile acid cotransporterIBA 01/2018
1	Eosine Yellowish-(YS) (Eosin)IBA 12/2017
1	Coloring Agents (Dyes)IBA 12/2017
1	Hematoxylin (Haematoxylon)IBA 12/2017
1	Reticulin (Reticular Fiber)IBA 12/2017
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 10/2017
1	Vinblastine (Vinblastine Sulfate)FDA Link 08/2017
1	Paclitaxel (Taxol)FDA LinkGeneric 08/2017
1	JNJ38877605IBA 08/2017
1	5- ((2,6- dichlorobenzyl)sulfonyl)- 3- ((3,5- dimethyl- 4- ((2- (pyrrolidin- 1- ylmethyl)pyrrolidin- 1- yl)carbonyl)- 1H- pyrrol- 2- yl)methylene)- 1,3- dihydro- 2H- indol- 2- oneIBA 08/2017
1	ARQ 197IBA 08/2017

Therapy/Procedure

6	Therapeutics 01/2020 - 09/2004
5	Liver Transplantation 01/2018 - 01/2002
3	Hepatectomy 04/2017 - 11/2005
3	Drug Therapy (Chemotherapy) 01/2014 - 05/2005
3	Contraception (Birth Control) 02/2013 - 03/2007
3	Radiotherapy 01/2008 - 05/2005
2	Radiofrequency Ablation 12/2013 - 11/2006
2	Chemoradiotherapy 04/2010 - 01/2008
1	Critical Care (Surgical Intensive Care) 11/2021
1	Lasers (Laser) 12/2017